microbiota

By liuwensen
March 29, 2017

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Primates are ideal hosts for studying variation in vaginal microbiota, because primate species differ markedly in their diet, anatomy, mating systems, gestational durations, birthing difficulties, and commensurate risks of maternal injury and subsequent infection (Rosenberg and Trevathan, 2002; Campbell et al., 2011).Primate vaginal microbiomes may also vary with exogenous host factors such as phylogeny, geography, life history characteristics and sexuality. The degree to which these factors explain variation in vaginal microbiota remains to be tested. However, if predictions can be drawn from other host systems, such as primate gut microbiomes (Ley et al., 2008; Ochman et al., 2010; Yildirim et al., 2010), patterns of microbial abundance and diversity are expected to be most similar between closely related primate species and differences should increase with phylogenetic distance (that is, vaginal microbial patterns reflect primate phylogeny).

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